![]() Pharmacists and nurses may also make significant contributions depending on the poisonous agent and necessary interventions or antidotes. The specialists involved will depend on the organ systems affected. Managing rodenticide toxicity requires an interprofessional team, including the emergency department, poison control, toxicologist, neurologist, intensivist, and possibly a nephrologist or hepatologist. Further treatment is often mainly supportive. Cholinergic toxicity may benefit from administering anticholinergic agents such as atropine, glycopyrrolate, and pralidoxime. Initiate cooling mechanisms such as evaporative cooling if severely hyperthermic such as in strychnine poisoning. If the patient presents within 30 to 60 minutes since ingestion, please call poison control immediately for the most updated guidelines.Īcute gastrointestinal effects may benefit from anti-emetics and rehydration to help correct electrolyte derangements. There is limited data that shows a decrease in morbidity and mortality. Gastric lavage and activated charcoal are not indicated in acute poisoning, according to the American Academy of Toxicology. Once the patient is stable and if they are visibly contaminated, then the next step involves removing clothes and irrigating the skin with water. Immediate management consists of supporting the airway, breathing, and circulation. It also highlights the interprofessional team's role in managing rodenticide toxicity patients. This activity outlines the evaluation and management of various types of rodenticide poisoning. In cases of serious ingestion, poison control and/or a medical toxicologist should be contacted. This step may involve staff returning to the point of potential exposure where the patient was last seen and searching for evidence of the rodenticide. ![]() ![]() ![]() When a clinician suspects rodenticide poisoning, every effort should be made to identify the substance, including package information (i.e., brand name, chemical name, signal word, presence of skull or crossbones on the label) and description (odor, appearance, color). Historically, heavy metals such as arsenic were the first agents used to control rodent populations, but the most common rodenticide used in the twenty-first century is anticoagulants. They are one of the most toxic agents commonly found in households. Rodenticides or "rat poisons" are mixed compounds used to eradicate rodents. ![]()
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